Sending Out an SOS: Updates in the Management of Sinusoidal Obstructive Syndrome

January 7, 2021

Given that SOS is a life-threatening complication, any delays or failure to recognize patients at risk can result in detrimental outcomes. The purpose of this activity is to equip pharmacists and pharmacist technicians with the knowledge of the most current updates in the recognition, risk assessment, severity grading, and the management of SOS. In March of 2020, the British Society of Hematology expert group published an update revealing new information on the pathogenesis, modifiable and unmodifiable risk factors for disease development, along with new revised diagnostic criteria, grading classification for SOS, and the evidence on the use of different prophylactic and therapeutic modalities. The early identification of the risk factors, more timely and accurate diagnosis and more innovative treatment approaches are crucial elements in improving patient survival. This presentation will summarize the new updates on SOS management and review the primary literature behind the newly published recommendations.

Target Audience

  • Pharmacists
  • Pharmacy technicians

Learning Objectives

Pharmacist learning objectives

  1. Describe the epidemiology and pathogenesis of sinusoidal obstructive syndrome
  2. Identify risk factors associated with the development of sinusoidal obstructive syndrome
  3. Evaluate revised diagnostic criteria and grading classification for sinusoidal obstructive syndrome
  4. Summarize the literature on the use of different prophylactic and therapeutic modalities for sinusoidal obstructive syndrome

Pharmacy technician learning objectives

  1. Recognize the brand/generic names of the agents used in the treatment and prevention of sinusoidal obstructive syndrome
  2. Review specific storage and stability requirements of the pharmacological preparations used to manage sinusoidal obstructive syndrome

Additional Information

Course summary
Available credit: 
  • 1.00 ACPE Pharmacist
  • 1.00 ACPE Pharmacy Technician
  • 1.00 General CE – Attendance
Course opens: 
Course expires: 
Event starts: 
01/07/2021 - 12:00pm CST
Event ends: 
01/07/2021 - 1:00pm CST
Ochsner Medical Center
New Orleans, LA
United States
Relevant financial relationships: Planning committee members and presenters have nothing to disclose
The presenter will discuss off-label use of drugs
Planning committee members
Jessica Foy, PharmD, BCOP
Clinical Oncology Pharmacist
Ochsner Medical Center
Bailey Wise, PharmD, BCPS
Clinical Pharmacist
Ochsner Medical Center
Course reviewer
James Lichauer, PharmD, BCPS, FASHP
PI Program Director, Pharmacy
Iryna Mialik, PharmD
PGY1 Pharmacy Practice Resident
Ochsner Medical Center
Joint Accreditation Statement:
In support of improving patient care, this activity has been planned and implemented by Vizient, Inc. and Ochsner Medical Center.  Vizient, Inc. is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Designation Statements:
Vizient, Inc. designates this activity for a maximum of 1.00 ACPE credit hours.
Universal Activity Number: JA0006103-9999-21-069-L01-P
Universal Activity Number: JA0006103-9999-21-069-L01-T
Vizient, Inc. will award CEUs to each participant who successfully completes this program. The CEU is a nationally recognized unit of measure for continuing education and training programs that meet certain criteria (1 contact hour = 0.1 CEU).

Available Credit

  • 1.00 ACPE Pharmacist
  • 1.00 ACPE Pharmacy Technician
  • 1.00 General CE – Attendance
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