2025 Vizient Pharmacy Network Meeting: Poster Session 3
Introduction/Purpose: Antimicrobial Stewardship Programs (ASPs) are designed to promote safe and effective use of antimicrobials to improve outcomes, reduce harm, and prevent antimicrobial resistance. Although the intravenous (IV) route is often used for its rapid onset and reliable bioavailability, prolonged use can increase hospital length of stay (LOS) and costs(1). Switching from IV to oral (PO) antibiotics once a patient is clinically stable, tolerating oral intake, and without contraindications is a key component of antimicrobial stewardship. Despite implementation of ASPs, studies show 45–75% of eligible patients are not transitioned to PO therapy when appropriate(2). Several studies evaluating impact of antimicrobial stewardship interventions on IV to PO conversion in hospitalized adults discovered conversion resulted in cost savings associated with decreased IV use and hospital LOS without increase in mortality or readmission rates(1,2). Furthermore, a multi-center study involving patients with sepsis in the Intensive Care Unit (ICU), found that IV to PO transition was associated with shorter ICU stays, reduced rates of acute kidney injury and antibiotic costs while showing no difference in mortality nor infection recurrence(3). This supports the idea that IV antibiotics can be safely transitioned to PO in critically ill patients. However, guidance is limited for IV to PO antibiotic conversion in this population resulting in missed opportunities for safe and effective transition to oral therapy in patients who are clinically stable. The purpose of this study is to improve Memorial Hermann – Texas Medical Center’s (MH-TMC) practices by piloting a MICU IV to PO conversion algorithm that helps identify eligible patients and promotes appropriate transitions to oral antimicrobials.
Purpose: Heart failure remains a leading cause of mortality, with a national 30-day hospital readmission rate of 21%. The economic impact is substantial, with national annual costs of approximately $30.7 billion. A significant barrier to optimizing transitions of care in patients is nonadherence to guideline-directed medical therapy (GDMT). Prior studies suggest that pharmacist involvement during transitions of care is associated with reduced readmissions and lower healthcare costs. Pharmacist-led discharge counseling and medication reconciliation (DCMR) is a potential strategy to improve medication adherence. DCMR can reduce 30-day readmissions and improve medication optimization in patients with heart failure following an exacerbation.
Obesity is a prevalent condition that significantly alters drug pharmacokinetics, leading to variability in absorption, distribution, metabolism, and elimination. When drug dosing is not tailored to body size, patients are placed at increased risk for both toxicity and treatment failure. Despite the clinical importance, current guidelines at Intermountain Health do not include obesity-specific recommendations, leaving a critical gap in practice and creating variability across providers and facilities.
Target Audience
- Pharmacists
- Pharmacy Technicians
- Other Healthcare Professionals
Learning Objectives
At the conclusion of this activity, pharmacists and pharmacy technicians should be able to:
- Apply data-driven insights and best practices to enhance medication management, improve patient outcomes, and support institutional performance goals
FACULTY & PLANNERS
PharmD, PGY-1 Pharmacy Resident
Jackson South Medical Center
PGY-1 Pharmacy Resident
Memorial Hermann - Texas Medical Center
PGY-1 Pharmacy Resident
Memorial Hermann - Texas Medical Center
PGY-1 Pharmacy Resident
Memorial Hermann - Texas Medical Center
Medstar Harbour Hospital
PGY2 Internal Medicine Pharmacy Resident
Intermountain Medical Center
Mital Desai, PharmD
Director, Pharmacy Network
Vizient, Inc.
Sybil Thomas, PharmD
AVP Member connections
Vizient, Inc.
Lauren E. McCree, MBA
Networks Manager, Pharmacy
Vizient, Inc.
Samantha Gordon, MS
CE Programs Manager
Vizient, Inc.
Marilu Kelly, MSN, RN, NPD-BC, CHCP
Director, Continuing Education
Vizient, Inc.
DISCLOSURE
Joint Accreditation Statement
In support of improving patient care, Vizient, Inc. is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.
Available Credit
- 0.75 ACPE Pharmacist
- 0.75 ACPE Pharmacy Technician
- If the "Register/Take Course" tab is displayed instead of the "Obtain Credit" tab, you must first login to proceed with the credit claim process.
- This activity requires learners to confirm their attendance using an activity code. An Access Denied error message indicates that your attendance was not recorded via SMS text or QR code scanning.
Required Hardware/software
The Vizient CE Learner Portal is compatible with most modern web browsers (such as Firefox, Google Chrome, Microsoft Edge, Apple Safari) and can also be accessed with mobile devices.

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